The Vesicle Protein SAM-4 Regulates the Processivity of Synaptic Vesicle Transport
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منابع مشابه
The Vesicle Protein SAM-4 Regulates the Processivity of Synaptic Vesicle Transport
Axonal transport of synaptic vesicles (SVs) is a KIF1A/UNC-104 mediated process critical for synapse development and maintenance yet little is known of how SV transport is regulated. Using C. elegans as an in vivo model, we identified SAM-4 as a novel conserved vesicular component regulating SV transport. Processivity, but not velocity, of SV transport was reduced in sam-4 mutants. sam-4 displa...
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ژورنال
عنوان ژورنال: PLoS Genetics
سال: 2014
ISSN: 1553-7404
DOI: 10.1371/journal.pgen.1004644